ESSENTIAL FUNCTION OF DICER IN RESOLVING DNA DAMAGE IN THE RAPIDLY DIVIDING CELLS OF THE DEVELOPING AND MALIGNANT CEREBELLUM

Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum

Maintenance of genomic integrity is critical during neurodevelopment, particularly in rapidly dividing cerebellar granule neuronal precursors that experience constitutive replication-associated DNA damage.As Dicer was recently recognized to have an unexpected function in the DNA damage response, we examined whether Dicer was important for preservin

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Meteorological conditions on Kaffiøyra (NW Spitsbergen) in 2013–2017 and their connection with atmospheric circulation and sea ice extent

This article comprises an analysis of the Procedure Towels variability of meteorological conditions on Kaffiøyra (NW Spitsbergen, Svalbard) in 2013–2017 in connection with atmospheric circulation and the extent of sea ice.The obtained results were compared with the results of observations made at the Ny-Ålesund station.Due to the situation of t

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Necroptosis and Neuroinflammation in Retinal Degeneration

Necroptosis mediates the chronic inflammatory phenotype BNC in neurodegeneration.Receptor-interacting protein kinase (RIPK) plays a pivotal role in the induction of necroptosis in various cell types, including microglia, and it is implicated in diverse neurodegenerative diseases in the central nervous system and the retina.Targeting RIPK has been p

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